Figure 19 is a metagraph depicting the effect of haloperidol versus quetiapine on general psychopathology in patients with Sz. Two trials (n=232) reported no significant difference between groups using the CDS-S (MD=0.03, 95 percent CI, −0.52, 0.58). Four trials (n=393) reported no significant difference between groups using PANSS scale (MD=0.46, 95 percent CI, −0.87, 1.78). Minimal heterogeneity existed between studies (p=0.35, I2=9%).

Figure 19Haloperidol versus quetiapine – General psychopathology

CDS–S = Calgary Depression Scale for Schizophrenia; CI = confidence intervals; df = degrees of freedom; I2 = I-squared; IV = inverse variance; PANSS = Positive and Negative Symptom Scale; SD = standard deviation

From: Results

Cover of First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 63.
Abou-Setta AM, Mousavi SS, Spooner C, et al.

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