TABLE 1Survey of the First 45 and the First 61 “Rat” Papers Published in Toxicology and Applied Pharmacology in 1979 and 1999

No. of papers4561
Used inbreds3(7)19(31)
Used outbredsa42(93)43(70)
Use strain/stock
Strain in title/abstractb8(18)27(44)
Used more than 1 strain1(2)4(7)
Able to find new genetic variationc0(0)0(0)

One paper used both.


Used as an indication of whether the author(s) considered that they were investigating “the rat” or a particular strain of rats.


Papers that used more than one strain comparatively when not investigating a known polymorphism.

From: Rat Genetics and Toxicology

Cover of Microbial Status and Genetic Evaluation of Mice and Rats
Microbial Status and Genetic Evaluation of Mice and Rats: Proceedings of the 1999 US/Japan Conference.
National Research Council (US) International Committee of the Institute for Laboratory Animal Research.
Washington (DC): National Academies Press (US); 2000.
Copyright © 2000, National Academy of Sciences.

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