Figure 1. . Urinary 2,8-dihydroxyadenine (DHA) crystals from an individual with adenine phosphoribosyltransferase deficiency.

Figure 1.

Urinary 2,8-dihydroxyadenine (DHA) crystals from an individual with adenine phosphoribosyltransferase deficiency. These crystals have a characteristic appearance and polarization pattern.

A. Conventional light microscopy shows the typical brown DHA crystals. Note the dark outline and central spicules (original magnification x 400).

B. The same field viewed with polarized light microscopy. The smaller crystals appear yellow and have a central Maltese cross pattern (original magnification x 400).

From: Adenine Phosphoribosyltransferase Deficiency

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