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Links from Nucleotide

Items: 1 to 20 of 562

1.

plasma membrane bounded cell projection

A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1510198
GO
: GO:0120025
2.

ligand-gated cation channel activity

Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1467752
GO
: GO:0099094
3.

BDNF-TrkB Signaling

Brain-derived neurotrophic factor (BDNF) is an important neurotrophin for the regulation of synaptic activity. BDNF-TrkB signaling, TrkB being the receptor of BDNF, is involved in transcription, translation, and trafficking of proteins in the various stages of synaptic development...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
4.

MECP2 and Associated Rett Syndrome

Mecp2 is in many mammals an important regulator of neuronal function and development. It affects all cell types, especially neurons but also astrocytes, oligodendrocytes, and glial cells. Mecp2 plays an important role in neuronal differentiation, maturation, morphology and function...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
5.

Common Pathways Underlying Drug Addiction

The pathway was modeled after Figure 2 in Li, et al. 2008 and is based on the common pathways identified in their study as well as protein interaction data. Specifically, glutamate and dopamine neuroactive ligand-receptor interactions trigger long-term potentiation, MAPK and GnRH...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
6.

neuron to neuron synapse

A synapse in which pre and post-synaptic cells are neurons.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1427935
GO
: GO:0098984
7.

RET signaling

The RET proto-oncogene encodes a receptor tyrosine kinase expressed primarily in urogenital precursor cells, spermatogonocytes, dopaminergic neurons, motor neurons and neural crest progenitors and derived cells. . It is essential for kidney genesis, spermatogonial self-renewal and...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
8.

Interactions of neurexins and neuroligins at synapses

Neurexins (NRXNs) and neuroligins (NLGNs) are best characterized synaptic cell-adhesion molecules. They are part of excitatory glutamatergic and inhibitory GABAergic synapses in mammalian brain, mediate trans-synaptic signaling, and shape neural network properties by specifying synaptic...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
9.

Protein-protein interactions at synapses

Synapses constitute highly specialized sites of asymmetric cell-cell adhesion and intercellular communication. Its formation involves the recruitment of presynaptic and postsynaptic molecules at newly formed contacts. Synapse assembly and maintenance invokes heterophilic presynaptic...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
10.

postsynaptic neurotransmitter receptor activity

Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission. Synonym: neurotransmitter receptor activity involved in chemical synaptic transmission.;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1402045
GO
: GO:0098960
11.

neurotransmitter receptor complex

Any protein complex that is capable of functioning as a neurotransmitter receptor.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1400654
GO
: GO:0098878
12.

anterograde trans-synaptic signaling

Cell-cell signaling from pre to post-synapse, across the synaptic cleft

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1388824
GO
: GO:0098916
13.

cell surface receptor signaling pathway involved in cell-cell signaling

Any cell surface receptor signaling pathway that is involved in cell-cell signaling. Synonyms: cell surface receptor linked signal transduction involved in cell-cell signaling; cell surface receptor linked signal transduction involved in cell-cell signalling; cell surface receptor...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1384661
GO
: GO:1905114
14.

intracellular vesicle

Any vesicle that is part of the intracellular region.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1384516
GO
: GO:0097708
15.

SALM protein interactions at the synapses

Recruitment of receptors and ion channels to the postsynaptic membrane is the last step in synapse formation. Many of these proteins interact directly or indirectly with postsynaptic density-95 (PSD95)/Discs large/zona occludens-1 (PDZ) proteins, thus linking them to the postsynaptic...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
16.

postsynaptic specialization membrane

The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1354132
GO
: GO:0099634
17.

transmembrane receptor activity

Combining with an extracellular or intracellular signal and transmitting a signal from one side of the membrane to the other.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1353948
GO
: GO:0099600
18.

postsynaptic specialization

A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal component...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1347044
GO
: GO:0099572
19.

chemical synaptic transmission, postsynaptic

The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. Synonym: postsynaptic process...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1347038
GO
: GO:0099565
20.

trans-synaptic signaling

Cell-cell signaling in either direction across the synaptic cleft.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1347010
GO
: GO:0099537

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