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heterotrimeric G-protein complex

Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein. Synonyms: heterotrimeric G-protein GTPase activity; heterotrimeric G-protein GTPase, alpha-subunit; heterotrimeric G-protein GTPase, beta-subunit; heterotrimeric G-protein GTPase, gamma-subunit;

from GO source record: GO:0005834
Type: structural_complex
Taxonomic scope
conserved biosystem

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