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Items: 13

1.

Kupffer's vesicle development

The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
515059
GO
: GO:0070121
2.

cilium assembly

The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. Synonyms:...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
513827
GO
: GO:0060271
3.

lipoprotein transport

The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
506047
GO
: GO:0042953
4.

ciliary transition zone

A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
505038
GO
: GO:0035869
5.

visual perception

The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. Synonyms: sense of sight; sensory visual...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
492342
GO
: GO:0007601
6.

small GTPase mediated signal transduction

Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. Synonym: small GTPase-mediated signal transduction;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
492043
GO
: GO:0007264
7.

lipid binding

Interacting selectively and non-covalently with a lipid.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
491521
GO
: GO:0008289
8.

centrosome

A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490839
GO
: GO:0005813
9.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490711
GO
: GO:0005737
10.

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
490627
GO
: GO:0005525
11.

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). Synonyms: GO:0045308; alpha-2 macroglobulin receptor-associated protein activity; protein amino acid binding; protein degradation...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486730
GO
: GO:0005515
12.

Trafficking of myristoylated proteins to the cilium

A number of myristoylated proteins have been shown to traffic to the cilium in a myristoyl- and UNC119B:ARL3:RP2-dependent fashion. These include the ciliary proteins Nephrocystin 3 (NPHP3) and Cystin 1 (CYS1) (Wright et al, 2011; reviewed in Schwarz et al, 2012). Myristoyl-binding...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
13.

Cargo trafficking to the periciliary membrane

Proteomic studies suggest that the cilium is home to approximately a thousand proteins, and has a unique protein and lipid make up relative to the bulk cytoplasm and plasma membrane (Pazour et al, 2005; Ishikawa et al, 2012; Ostrowoski et al, 2002; reviewed in Emmer et al, 2010; Rohatgi...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens

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