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Items: 8

1.

centrosome duplication

The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. Synonym: centrosome replication;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
512183
GO
: GO:0051298
2.

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
500433
GO
: GO:0031146
3.

negative regulation of centrosome duplication

Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
494890
GO
: GO:0010826
4.

SCF ubiquitin ligase complex

A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
493942
GO
: GO:0019005
5.

centriole

A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490840
GO
: GO:0005814
6.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490701
GO
: GO:0005634
7.

protein ubiquitination

The process in which one or more ubiquitin groups are added to a protein. Synonyms: protein ubiquitinylation; protein ubiquitylation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
490646
GO
: GO:0016567
8.

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). Synonyms: GO:0045308; alpha-2 macroglobulin receptor-associated protein activity; protein amino acid binding; protein degradation...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486730
GO
: GO:0005515

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