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Items: 10

1.

protein K63-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
515464
GO
: GO:0070534
2.

protein autoubiquitination

The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink. Synonyms: protein auto-ubiquitination; protein auto-ubiquitinylation; protein autoubiquitinylation;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
512723
GO
: GO:0051865
3.

positive regulation of NF-kappaB transcription factor activity

Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB. Synonyms: NF-kappaB activation; activation of NF-kappaB; activation of NF-kappaB transcription factor;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
512006
GO
: GO:0051092
4.

sphingolipid binding

Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
508873
GO
: GO:0046625
5.

positive regulation of NF-kappaB import into nucleus

Any process that activates or increases the frequency, rate or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. Synonyms: activation of NF-kappaB import into nucleus;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
505490
GO
: GO:0042346
6.

positive regulation of protein ubiquitination

Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein. Synonyms: activation of protein ubiquitination; stimulation of protein ubiquitination; up regulation of protein ubiquitination; up-regulation of protein ubiquitination;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
500649
GO
: GO:0031398
7.

D-erythro-sphingosine kinase activity

Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP. Synonym: sphingosine kinase activity;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
496871
GO
: GO:0017050
8.

regulation of tumor necrosis factor-mediated signaling pathway

Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. Synonyms:...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
494867
GO
: GO:0010803
9.

sphingosine metabolic process

The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. Synonyms: (4E)-sphing-4-enine metabolic process; (4E)-sphing-4-enine...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491558
GO
: GO:0006670
10.

ubiquitin-protein transferase activity

Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. Synonyms: E2; E3; GO:0004840; GO:0004841; anaphase-promoting complex activity; ubiquitin conjugating enzyme activity; ubiquitin...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
490144
GO
: GO:0004842

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