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Items: 16

1.

positive regulation of canonical Wnt signaling pathway

Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518403
GO
: GO:0090263
2.

negative regulation of canonical Wnt signaling pathway

Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518230
GO
: GO:0090090
3.

cytoplasmic sequestering of protein

The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell. Synonyms: cytoplasmic retention of protein; cytoplasmic sequestration of protein; cytoplasmic storage of protein; maintenance of protein...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
512116
GO
: GO:0051220
4.

protein serine/threonine kinase activator activity

Binds to and increases the activity of a protein serine/threonine kinase. Synonym: protein ser/thr kinase activator activity;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
506570
GO
: GO:0043539
5.

regulation of protein complex assembly

Any process that modulates the frequency, rate or extent of protein complex assembly.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
506321
GO
: GO:0043254
6.

negative regulation of catenin import into nucleus

Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus. Synonym: negative regulation of catenin protein nuclear translocation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
504598
GO
: GO:0035414
7.

hippo signaling

The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki)...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
504513
GO
: GO:0035329
8.

positive regulation of peptidyl-serine phosphorylation

Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
502359
GO
: GO:0033138
9.

cell junction

A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
499502
GO
: GO:0030054
10.

negative regulation of protein kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. Synonyms: down regulation of protein kinase activity; down-regulation of protein kinase activity; downregulation of protein kinase activity; inhibition of protein kinase activit...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491372
GO
: GO:0006469
11.

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490711
GO
: GO:0005737
12.

protein serine/threonine kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Synonyms: GO:0004695; GO:0004696; GO:0004700; protein kinase (phosphorylating) activity; protein phosphokinase activity; protein serine...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
490001
GO
: GO:0004674
13.

positive regulation of protein phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. Synonyms: activation of protein amino acid phosphorylation; positive regulation of protein amino acid phosphorylation; stimulation of protein amino...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487825
GO
: GO:0001934
14.

negative regulation of protein phosphorylation

Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. Synonyms: down regulation of protein amino acid phosphorylation; down-regulation of protein amino acid phosphorylation; downregulation of protein amino acid phosphorylation;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487824
GO
: GO:0001933
15.

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). Synonyms: GO:0045308; alpha-2 macroglobulin receptor-associated protein activity; protein amino acid binding; protein degradation...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486730
GO
: GO:0005515
16.

Signaling by Hippo

Human Hippo signaling is a network of reactions that regulates cell proliferation and apoptosis, centered on a three-step kinase cascade. The cascade was discovered by analysis of Drosophila mutations that lead to tissue overgrowth, and human homologues of its components have since...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens

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