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Items: 6

1.

stem cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
510912
GO
: GO:0048863
2.

ESC/E(Z) complex

A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. Synonyms: Extra...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
504283
GO
: GO:0035098
3.

negative regulation of histone methylation

Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones. Synonyms: down regulation of histone methylation; down-regulation of histone methylation; downregulation of histone methylation; inhibition of histone...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
500351
GO
: GO:0031061
4.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490701
GO
: GO:0005634
5.

chromatin binding

Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. Synonyms: lamin/chromatin binding; microtubule/chromatin interaction; nuclear membrane vesicle...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
489235
GO
: GO:0003682
6.

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). Synonyms: GO:0045308; alpha-2 macroglobulin receptor-associated protein activity; protein amino acid binding; protein degradation...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486730
GO
: GO:0005515

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