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Items: 14

1.

ubiquitin protein ligase activity

Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
987826
GO
: GO:0061630
2.

negative regulation of release of cytochrome c from mitochondria

Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activa...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518341
GO
: GO:0090201
3.

positive regulation of release of cytochrome c from mitochondria

Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activa...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518340
GO
: GO:0090200
4.

protein K63-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
515464
GO
: GO:0070534
5.

C3HC4-type RING finger domain binding

Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C,...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
513558
GO
: GO:0055131
6.

regulation of protein complex assembly

Any process that modulates the frequency, rate or extent of protein complex assembly.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
506321
GO
: GO:0043254
7.

positive regulation of I-kappaB kinase/NF-kappaB signaling

Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling. Synonyms: activation of I-kappaB kinase/NF-kappaB cascade; positive regulation of I-kappaB kinase/NF-kappaB cascade; stimulation of I-kappaB kinase/NF-kappaB cascade; up regulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
506197
GO
: GO:0043123
8.

regulation of protein ubiquitination

Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
500647
GO
: GO:0031396
9.

kinase binding

Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
498677
GO
: GO:0019900
10.

peptidyl-serine phosphorylation

The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
497080
GO
: GO:0018105
11.

calcium-dependent protein kinase activity

Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
494921
GO
: GO:0010857
12.

protein serine/threonine kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Synonyms: GO:0004695; GO:0004696; GO:0004700; protein kinase (phosphorylating) activity; protein phosphokinase activity; protein serine...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
490001
GO
: GO:0004674
13.

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
489957
GO
: GO:0005829
14.

protein polyubiquitination

Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. Synonyms: polyubiquitin; protein polyubiquitinylation; protein polyubiquitylation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
486728
GO
: GO:0000209

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