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Items: 5

1.

sequence-specific DNA binding

Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. Synonym: sequence specific DNA binding;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
506596
GO
: GO:0043565
2.

transcription factor complex

A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490724
GO
: GO:0005667
3.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490701
GO
: GO:0005634
4.

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II. Synonyms: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
489251
GO
: GO:0003705
5.

negative regulation of transcription from RNA polymerase II promoter

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter. Synonyms: GO:0010553; GO:0045816; down regulation of global transcription from RNA polymerase II promoter; down regulation of transcription from RNA polymerase...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
486661
GO
: GO:0000122

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