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Items: 12

1.

positive regulation of transcription from RNA polymerase II promoter

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. Synonyms: GO:0010552; GO:0045817; activation of global transcription from RNA polymerase II promoter; activation of transcription from RNA polymerase II promoter;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
508249
GO
: GO:0045944
2.

negative regulation of DNA damage response, signal transduction by p53 class mediator

Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. Synonyms: down regulation of DNA damage response, signal...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
506549
GO
: GO:0043518
3.

negative regulation of sequence-specific DNA binding transcription factor activity

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. Synonyms: down regulation of transcription factor activity; down-regulation of transcription...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
506470
GO
: GO:0043433
4.

NAD-dependent protein deacetylase activity

Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
504171
GO
: GO:0034979
5.

enzyme binding

Interacting selectively and non-covalently with any enzyme.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
496935
GO
: GO:0019899
6.

negative regulation of transcription, DNA-templated

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. Synonyms: GO:0016481; GO:0032582; GO:0061021; down regulation of gene-specific transcription; down regulation of transcription, DNA-dependent; down-regulation of gene-specific...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
496515
GO
: GO:0045892
7.

cell aging

An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
492319
GO
: GO:0007569
8.

protein deacetylation

The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. Synonym: protein amino acid deacetylation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
491378
GO
: GO:0006476
9.

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
490701
GO
: GO:0005634
10.

p53 binding

Interacting selectively and non-covalently with one of the p53 family of proteins.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
487929
GO
: GO:0002039
11.

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). Synonyms: GO:0045308; alpha-2 macroglobulin receptor-associated protein activity; protein amino acid binding; protein degradation...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
486730
GO
: GO:0005515
12.

Signaling events mediated by HDAC Class III

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens

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