Display Settings:


Send to:

Choose Destination

Links from PubMed

Nef mediated downregulation of MHC class I complex cell surface expression

Down-regulation of MHC class I involves Nef-mediated connection in the endosomes between MHC-I's cytoplasmic tail and the phosphofurin acidic cluster sorting protein-1 (PACS-1)-dependent protein-sorting pathway. Down-regulation of MHC I protects HIV-infected cells from host CTL response.

from REACTOME source record: R-HSA-164940
Type: pathway
Taxonomic scope
organism-specific biosystem
Homo sapiens

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center