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Links from Protein

Items: 1 to 20 of 219

1.

Activation of anterior HOX genes in hindbrain development during early embryogenesis

In mammals, anterior Hox genes may be defined as paralog groups 1 to 4 (Natale et al. 2011), which are involved in development of the hindbrain through sequential expression in the rhombomeres, transient segments of the neural tube that form during development of the hindbrain (reviewed...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
2.

MECP2 and Associated Rett Syndrome

Mecp2 is in many mammals an important regulator of neuronal function and development. It affects all cell types, especially neurons but also astrocytes, oligodendrocytes, and glial cells. Mecp2 plays an important role in neuronal differentiation, maturation, morphology and function...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
3.

Activation of HOX genes during differentiation

Hox genes encode proteins that contain the DNA-binding homeobox motif and control early patterning of segments in the embryo as well as later events in development (reviewed in Rezsohazy et al. 2015). Mammals have 39 Hox genes arrayed in 4 linear clusters, with each cluster containing...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
4.

Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways

In this model, we provide an integrated view of Sudden Infant Death Syndrome (SIDS) at the level of implicated tissues, signaling networks and genetics. The purpose of this model is to serve as an overview of research in this field and recommend new candidates for more focused or...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
5.

Developmental Biology

As a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are aspects of the roles of cell adhesion molecules in axonal guidance and myogenesis,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
6.

sequence-specific double-stranded DNA binding

Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. Synonym: sequence-specific dsDNA binding;

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
1310813
GO
: GO:1990837
7.

negative regulation of nucleic acid-templated transcription

Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription. Synonyms: down regulation of nucleic acid-templated transcription; down-regulation of nucleic acid-templated transcription; downregulation of nucleic acid-templated transcription;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129334
GO
: GO:1903507
8.

regulation of nucleic acid-templated transcription

Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129333
GO
: GO:1903506
9.

negative regulation of RNA biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. Synonyms: down regulation of RNA anabolism; down regulation of RNA biosynthesis; down regulation of RNA biosynthetic process; down regulation of RNA formation; down regulation of...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
948122
GO
: GO:1902679
10.

regulation of chromatin organization

Any process that modulates the frequency, rate or extent of chromatin organization. Synonyms: GO:1903308; regulation of chromatin modification; regulation of chromatin organisation; regulation of establishment or maintenance of chromatin architecture;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
849976
GO
: GO:1902275
11.

regulation of RNA biosynthetic process

Any process that modulates the frequency, rate or extent of RNA biosynthetic process. Synonyms: regulation of RNA anabolism; regulation of RNA biosynthesis; regulation of RNA formation; regulation of RNA synthesis;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
755247
GO
: GO:2001141
12.

organic cyclic compound binding

Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
752660
GO
: GO:0097159
13.

single-organism developmental process

A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
751909
GO
: GO:0044767
14.

transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding

Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter. Synonym: RNA polymerase II transcription...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
750780
GO
: GO:0001228
15.

transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding

Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. Synonym: RNA polymerase II transcription...

Type
:
functional_set
Taxonomic scope
:
conserved biosystem
BSID:
750779
GO
: GO:0001227
16.

genetic imprinting

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516438
GO
: GO:0071514
17.

protein localization to chromosome, centromeric region

Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome. Synonyms: protein localisation to chromosome, centromeric region; protein localization to centromere; protein localization to chromosome, centric region;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516383
GO
: GO:0071459
18.

DNA conformation change

A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. Synonym: DNA conformation modification;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
516029
GO
: GO:0071103
19.

regulation of centromeric sister chromatid cohesion

Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome. Synonym: regulation of sister chromatid cohesion at centromere;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
515532
GO
: GO:0070602
20.

biological regulation

Any process that modulates a measurable attribute of any biological process, quality or function. Synonym: regulation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
514938
GO
: GO:0065007

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