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Links from Protein

Items: 1 to 20 of 362

1.

Breast cancer

Breast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gland. The molecular subtypes of breast cancer, which are based on the presence or absence...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
2.

Prolactin signaling pathway

Prolactin (PRL) is a polypeptide hormone known to be involved in a wide range of biological functions including osmoregulation, lactation, reproduction, growth and development, endocrinology and metabolism, brain and behavior, and immunomodulation. PRL mediates its action through...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
3.

NF-kappa B signaling pathway

Nuclear factor-kappa B (NF-kappa B) is the generic name of a family of transcription factors that function as dimers and regulate genes involved in immunity, inflammation and cell survival. There are several pathways leading to NF-kappa B-activation. The canonical pathway is induced...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
4.

Rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune system elevates pro-inflammatory cytokines and chemokines levels, which can promote...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
5.

Osteoclast differentiation

The osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways activated by RANK and immune receptors, whose ligands are expressed on the surface...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
6.

Cytokine-cytokine receptor interaction

Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
7.

Breast cancer

Breast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gland. The molecular subtypes of breast cancer, which are based on the presence or absence...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
8.

TNFs bind their physiological receptors

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
9.

TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
10.

Prolactin signaling pathway

Prolactin (PRL) is a polypeptide hormone known to be involved in a wide range of biological functions including osmoregulation, lactation, reproduction, growth and development, endocrinology and metabolism, brain and behavior, and immunomodulation. PRL mediates its action through...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
11.

NF-kappa B signaling pathway

Nuclear factor-kappa B (NF-kappa B) is the generic name of a family of transcription factors that function as dimers and regulate genes involved in immunity, inflammation and cell survival. There are several pathways leading to NF-kappa B-activation. The canonical pathway is induced...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
12.

Rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affects bone remodeling leading to progressive bone destruction. In RA, abnormal activation of the immune system elevates pro-inflammatory cytokines and chemokines levels, which can promote...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
13.

Osteoclast differentiation

The osteoclasts, multinucleared cells originating from the hematopoietic monocyte-macrophage lineage, are responsible for bone resorption. Osteoclastogenesis is mainly regulated by signaling pathways activated by RANK and immune receptors, whose ligands are expressed on the surface...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
14.

Cytokine-cytokine receptor interaction

Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
15.

TNFR2 non-canonical NF-kB pathway

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
16.

Cytokine Signaling in Immune system

computationally inferred pathway (not manually curated)

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Mus musculus
17.

regulation of hemopoiesis

Any process that modulates the frequency, rate or extent of hemopoiesis. Synonyms: regulation of blood cell biosynthesis; regulation of blood cell formation; regulation of haemopoiesis; regulation of hematopoiesis;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129530
GO
: GO:1903706
18.

regulation of nucleic acid-templated transcription

Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129333
GO
: GO:1903506
19.

positive regulation of leukocyte cell-cell adhesion

Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. Synonyms: activation of leukocyte adhesion; activation of leukocyte cell adhesion; activation of leukocyte cell-cell adhesion; positive regulation of leukocyte adhesion; positive...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
987840
GO
: GO:1903039
20.

positive regulation of bone development

Any process that activates or increases the frequency, rate or extent of bone development. Synonyms: activation of bone development; up regulation of bone development; up-regulation of bone development; upregulation of bone development;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
983731
GO
: GO:1903012

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