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Links from Nucleotide

Items: 1 to 20 of 616

1.

Angiopoietin Like Protein 8 Regulatory Pathway

The hepatic ANGPTL8 (Angiopoietin Like Protein 8) regulatory pathway represents an up-to-date curated interactive pathway for all of the interactions from the known regulators of ANGPTL8 and updated signaling events of insulin signaling in the liver.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
2.

positive regulation of protein localization to membrane

Any process that activates or increases the frequency, rate or extent of protein localization to membrane. Synonyms: activation of protein localisation in membrane; activation of protein localization in membrane; activation of protein localization to membrane; positive regulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1458715
GO
: GO:1905477
3.

regulation of protein localization to membrane

Any process that modulates the frequency, rate or extent of protein localization to membrane. Synonyms: regulation of protein localisation in membrane; regulation of protein localization in membrane;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1458713
GO
: GO:1905475
4.

Cardiac Hypertrophic Response

Integrated schematic of the more extensively characterized intracellular signal-transduction pathways that coordinate the cardiac hypertrophic response. During development and in response to physiological stimuli or pathological insults, the heart undergoes hypertrophic enlargement,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
5.

neuron to neuron synapse

A synapse in which pre and post-synaptic cells are neurons.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1427935
GO
: GO:0098984
6.

Platinum drug resistance

Platinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of solid malignancies, including testicular, ovarian, head and neck, colorectal, bladder and lung cancers. The mechanism of action of Platinum-based drugs involves covalent binding to purine...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
7.

Platinum drug resistance

Platinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of solid malignancies, including testicular, ovarian, head and neck, colorectal, bladder and lung cancers. The mechanism of action of Platinum-based drugs involves covalent binding to purine...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
8.

intracellular vesicle

Any vesicle that is part of the intracellular region.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1384516
GO
: GO:0097708
9.

Regulation of TP53 Degradation

In unstressed cells, TP53 (p53) has a short half-life as it undergoes rapid ubiquitination and proteasome-mediated degradation. The E3 ubiquitin ligase MDM2, which is a transcriptional target of TP53, plays the main role in TP53 protein down-regulation (Wu et al. 1993). MDM2 forms...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
10.

Regulation of TP53 Expression and Degradation

TP53 (p53) tumor suppressor protein is a transcription factor that functions as a homotetramer (Jeffrey et al. 1995). The protein levels of TP53 are low in unstressed cells due to MDM2-mediated ubiquitination that triggers proteasome-mediated degradation of TP53 (Wu et al. 1993)....

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
11.

Regulation of TP53 Activity

Protein stability and transcriptional activity of TP53 (p53) tumor suppressor are regulated by post-translational modifications that include ubiquitination, phosphorylation, acetylation, methylation, sumoylation and prolyl-isomerization (Kruse and Gu 2009, Meek and Anderson 2009,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
12.

positive regulation of establishment of protein localization

Any process that activates or increases the frequency, rate or extent of establishment of protein localization. Synonyms: activation of establishment of protein localisation; activation of establishment of protein localization; activation of protein positioning; activation of protein...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1348614
GO
: GO:1904951
13.

postsynaptic specialization

A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal component...

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1347044
GO
: GO:0099572
14.

trans-synaptic signaling

Cell-cell signaling in either direction across the synaptic cleft.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1347010
GO
: GO:0099537
15.

synaptic signaling

Cell-cell signaling to or from a synapse.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1347009
GO
: GO:0099536
16.

Insulin resistance

Insulin resistance is a condition where cells become resistant to the effects of insulin. It is often found in people with health disorders, including obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular diseases. In this diagram multiple mechanisms...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
17.

positive regulation of calcium ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport. Synonyms: activation of calcium ion membrane transport; activation of calcium ion transmembrane transport; activation of transmembrane calcium transport; positive regulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1272353
GO
: GO:1904427
18.

positive regulation of protein localization to cell periphery

Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. Synonyms: activation of protein localization to cell periphery; up regulation of protein localization to cell periphery; up-regulation of protein localization to cell periphery;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1272303
GO
: GO:1904377
19.

regulation of protein localization to cell periphery

Any process that modulates the frequency, rate or extent of protein localization to cell periphery.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1272301
GO
: GO:1904375
20.

postsynapse

The part of a synapse that is part of the post-synaptic cell.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272068
GO
: GO:0098794

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