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Links from Nucleotide

Items: 1 to 20 of 203

1.

plasma membrane bounded cell projection

A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1510198
GO
: GO:0120025
2.

microtubule-based transport

A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1467769
GO
: GO:0099111
3.

Signaling by BRAF and RAF fusions

In addition to the more prevalent point mutations, BRAF and RAF1 are also subject to activation as a result of translocation events that yield truncated or fusion products (Jones et al, 2008; Cin et al, 2011; Palanisamy et al, 2010; Ciampi et al, 2005; Stransky et al, 2014; Hutchinson...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
4.

Oncogenic MAPK signaling

The importance of the RAS/RAF/MAPK cascade in regulating cellular proliferation, differentiation and survival is highlighted by the fact that components of the pathway are mutated with high frequency in a large number of human cancers. Activating mutations in RAS are found in approximately...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
5.

vesicle-mediated transport in synapse

Any vesicle-mediated transport that occurs in a synapse

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1427954
GO
: GO:0099003
6.

axonal transport

The directed movement of organelles or molecules along microtubules in axons. Synonyms: axon cargo transport; axoplasmic transport;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1402022
GO
: GO:0098930
7.

intracellular vesicle

Any vesicle that is part of the intracellular region.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1384516
GO
: GO:0097708
8.

cytoplasmic region

Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm"

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1347041
GO
: GO:0099568
9.

vesicle cytoskeletal trafficking

The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. Synonyms: cytoskeletal fiber-based vesicle localization; vesicle cytoskeletal transport;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1346991
GO
: GO:0099518
10.

synaptic vesicle transport along microtubule

The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1346990
GO
: GO:0099517
11.

synaptic vesicle cytoskeletal transport

The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1346987
GO
: GO:0099514
12.

lytic vacuole membrane

The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1310886
GO
: GO:0098852
13.

whole membrane

Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272078
GO
: GO:0098805
14.

membrane protein complex

Any protein complex that is part of a membrane.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1272070
GO
: GO:0098796
15.

Golgi Associated Vesicle Biogenesis

Proteins that have been synthesized, processed and sorted eventually reach the final steps of the secretory pathway. This pathway is responsible not only for proteins that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
16.

Clathrin derived vesicle budding

There at least two classes of clathrin coated vesicles in cells, one predominantly Golgi-associated, involved in budding from the trans-Golgi network and the other at the plasma membrane. Here the clathrin-coated vesicles emerging from the Golgi apparatus are triggered by the heterotetrameric...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
17.

trans-Golgi Network Vesicle Budding

After passing through the Golgi complex, secretory cargo is packaged into post-Golgi transport intermediates (post-Golgi), which translocate plus-end directed along microtubules to the plasma membrane.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
18.

Membrane Trafficking

The secretory membrane system allows a cell to regulate delivery of newly synthesized proteins, carbohydrates, and lipids to the cell surface, a necessity for growth and homeostasis. The system is made up of distinct organelles, including the endoplasmic reticulum (ER), Golgi complex,...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
19.

Vesicle-mediated transport

The transit of proteins and other cargo through the cell requires a cellular transport process in which transported substances are moved in membrane-bounded vesicles. Transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The transport process...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
20.

Diseases of signal transduction

Signaling processes are central to human physiology (e.g., Pires-da Silva & Sommer 2003), and their disruption by either germ-line and somatic mutation can lead to serious disease. Here, the molecular consequences of mutations affecting visual signal transduction and signaling by...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens

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