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Items: 1 to 20 of 149

1.

Neutrophil degranulation

Neutrophils are the most abundant leukocytes (white blood cells), indispensable in defending the body against invading microorganisms. In response to infection, neutrophils leave the circulation and migrate towards the inflammatory focus. They contain several subsets of granules that...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
2.

intracellular vesicle

Any vesicle that is part of the intracellular region.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1384516
GO
: GO:0097708
3.

secretory vesicle

A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1346976
GO
: GO:0099503
4.

ficolin-1-rich granule lumen

Any membrane-enclosed lumen that is part of a ficolin-1-rich granule. Synonyms: ficolin-1-rich granule membrane-enclosed lumen; membrane-enclosed lumen of ficolin granule; membrane-enclosed lumen of ficolin-1 rich granule; membrane-enclosed lumen of ficolin-1-rich granule;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1319027
GO
: GO:1904813
5.

ficolin-1-rich granule

Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry....

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1318985
GO
: GO:0101002
6.

HS-GAG degradation

Lysosomal degradation of glycoproteins is part of the cellular homeostasis of glycosylation (Winchester 2005). The steps outlined below describe the degradation of heparan sulfate/heparin. Complete degradation of glycoproteins is required to avoid build up of glycosaminoglycan fragments...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
7.

Heparan sulfate/heparin (HS-GAG) metabolism

The acronym HS-GAG is used to describe both heparin and heparan sulfate. HS-GAG is a member of the glycosaminoglycan family and consists of a variably sulfated repeating disaccharide unit, the most common one (50% of the total) being glucuronic acid (GlcA) linked to N-acetylglucosamine...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
8.

Hyaluronan uptake and degradation

Hyaluronan (HA) turnover can occur locally at the tissue of origin, where it is taken up by cells to be degraded, or released into the lymphatic and vascular systems, where it can be eliminated by the liver and kidneys. Uptake of HA into cells for degradation involves receptor-mediated...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
9.

Hyaluronan metabolism

Hyaluronan (hyaluronic acid, hyaluronate or HA) is an anionic glycosaminoglycan (GAG) distributed widely throughout connective, epithelial, and neural tissues and most abundant in the extracellular matrix and skin. HA is unique among the GAGs in that it is not sulfated and is not...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
10.

Glycosaminoglycan metabolism

Glycosaminoglycans (GAGs) are long, unbranched polysaccharides containing a repeating disaccharide unit composed of a hexosamine (either N-acetylgalactosamine (GalNAc) or N-acetylglucosamine (GlcNAc)) and a uronic acid (glucuronate or iduronate). They can be heavily sulfated. GAGs...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
11.

Metabolism of carbohydrates

These pathways together are responsible for: 1) the extraction of energy and carbon skeletons for biosyntheses from dietary sugars and related molecules; 2) the short-term storage of glucose in the body (as glycogen) and its mobilization during a short fast; and 3) the synthesis of...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
12.

Metabolism

Metabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as the inactivation and elimination of toxic ones generated endogenously or present in...

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
13.

Innate Immune System

Innate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
14.

Immune System

Humans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first critical hours and days of exposure to a new pathogen, our innate immune system.

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
15.

extracellular vesicle

Any vesicle that is part of the extracellular region. Synonym: microparticle;

Type
:
structural_complex
Taxonomic scope
:
conserved biosystem
BSID:
1129387
GO
: GO:1903561
16.

mucopolysaccharide metabolic process

The chemical reactions and pathways involving mucopolysaccharide. Synonym: mucopolysaccharide metabolism;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
1129337
GO
: GO:1903510
17.

Glucuronate pathway (uronate pathway)

Pathway module; Carbohydrate and lipid metabolism; Other carbohydrate metabolism

Type
:
pathway
Taxonomic scope
:
organism-specific biosystem
Organism
:
Homo sapiens
18.

single-organism localization

A localization which involves only one organism. Synonym: single organism localization;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
925927
GO
: GO:1902578
19.

glycosyl compound catabolic process

The chemical reactions and pathways resulting in the breakdown of glycosyl compound. Synonyms: glycosyl compound breakdown; glycosyl compound catabolism; glycosyl compound degradation;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
754610
GO
: GO:1901658
20.

glycosyl compound metabolic process

The chemical reactions and pathways involving glycosyl compound. Synonym: glycosyl compound metabolism;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
754609
GO
: GO:1901657

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