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Items: 1 to 20 of 2040

1.

regulation of replicative cell aging

Any process that modulates the frequency, rate or extent of replicative cell aging. Synonym: regulation of replicative cell ageing;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
753058
GO
: GO:1900062
2.

negative regulation of cell aging

Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518484
GO
: GO:0090344
3.

positive regulation of cell aging

Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518483
GO
: GO:0090343
4.

regulation of cell aging

Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
518482
GO
: GO:0090342
5.

aging

A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
492318
GO
: GO:0007568
6.

progressive alteration of chromatin involved in replicative cell aging

A process that results in changes in chromatin structure contributing to replicative cell aging. Synonyms: progressive alteration of chromatin during replicative cell ageing; progressive alteration of chromatin during replicative cell aging;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487405
GO
: GO:0001304
7.

progressive alteration of chromatin involved in chronological cell aging

A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells. Synonyms: progressive alteration of chromatin during chronological cell ageing; progressive alteration of chromatin during chronological cell aging;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487406
GO
: GO:0001305
8.

nucleolar fragmentation involved in replicative aging

A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells. Synonyms: nucleolar fragmentation during replicative ageing; nucleolar fragmentation during replicative aging;

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487404
GO
: GO:0001303
9.

multicellular organism aging

An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
494333
GO
: GO:0010259
10.

inheritance of oxidatively modified proteins involved in replicative cell aging

A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells. Synonyms: inheritance of oxidatively modified proteins during replicative cell ageing; inheritance...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487420
GO
: GO:0001319
11.

extrachromosomal circular DNA localization involved in cell aging

A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging. Synonyms: extrachromosomal circular DNA localisation involved in cell aging; extrachromosomal circular DNA localization during...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
503852
GO
: GO:0034652
12.

regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction

Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus.

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
752177
GO
: GO:0061434
13.

negative regulation of chromatin silencing involved in replicative cell aging

The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins. Synonyms: loss of chromatin silencing during replicative cell ageing; loss of chromatin silencing involved in replicative cell...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487409
GO
: GO:0001308
14.

regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging

Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging. Synonyms: regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing; regulation of extrachromosomal rDNA circle accumulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
753007
GO
: GO:1900007
15.

formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging

Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age. Synonyms: assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging; formation of extrachromosomal circular rDNA...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487412
GO
: GO:0001311
16.

progressive alteration of chromatin involved in cell aging

Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype. Synonyms: age-dependent accumulation...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487402
GO
: GO:0001301
17.

cell aging

An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
492319
GO
: GO:0007569
18.

formation of extrachromosomal circular DNA involved in replicative cell aging

Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age. Synonyms: assembly of extrachromosomal circular DNA involved in replicative cell aging;...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487414
GO
: GO:0001313
19.

accumulation of oxidatively modified proteins involved in replicative cell aging

Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking. Synonyms: accumulation of oxidatively modified...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487418
GO
: GO:0001317
20.

replication of extrachromosomal circular DNA involved in replicative cell aging

Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication. Synonyms: replication of extrachromosomal circular DNA during replicative cell...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
487415
GO
: GO:0001314

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