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Items: 2

1.

Mismatch repair

DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
2.

Fanconi anemia pathway

The Fanconi anemia pathway is required for the efficient repair of damaged DNA, especially interstrand cross-links (ICLs). DNA ICL is directly recognized by FANCM and associated proteins, that recruit the FA core complex. The FA core complex monoubiquitinates FANCD2 and FANCI. The...

Type
:
pathway
Taxonomic scope
:
conserved biosystem
BSID:
377128
KEGG
: ko03460

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