Display Settings:


Send to:

Choose Destination

Insulin receptor signalling cascade

Autophosphorylation of the insulin receptor triggers a series of signalling events, mediated by SHC or IRS, and resulting in activation of the Ras/RAF and MAP kinase cascades. A second effect of the autophosphorylation of the insulin receptor is its internalisation into an endosome, which downregulates its signalling activity.

from REACTOME source record: R-HSA-74751
Type: pathway
Taxonomic scope
organism-specific biosystem
Homo sapiens

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center