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Accession: PRJNA132993 ID: 132993

Mus musculus (house mouse)

CpG B and R848 induced gene expression in IRAK2 wildtype and deficient mouse macrophages

See Genome Information for Mus musculus
Compared to wildtype macrophages, IRAK2 deficient macrophages show higher induced gene expression in responsse to CpG B, but not R848 Manuscipt title: The dual function of IRAK2 in TLR9-mediated interfereon and proinflammatory cytokine production Overall design: Bone marrow derived macrophages from wildtype and IRAK2 knockout mouse were stimulated with CpG B or R848 for 2 hours, or untreated.
AccessionPRJNA132993; GEO: GSE24264
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsWan Y et al., "The dual functions of IL-1 receptor-associated kinase 2 in TLR9-mediated IFN and proinflammatory cytokine production.", J Immunol, 2011 Jan 26;186(5):3006-14
SubmissionRegistration date: 23-Sep-2010
Xiaoxia Li, Immunology, Cleveland Clinic Foundation
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots154182
Data volume, Processed Mbytes4
Data volume, Supplementary Mbytes1

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