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3 additional projects are components of the Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath.
Here, we describe CRISPRpath, a CRISPR screening strategy for simultaneously characterizing CREs in multiple genomic loci by leveraging converging phenotypes resulted from transcriptional defects in genes linked to the same biological pathway.
Overall design: Examination of gene expression with RNA-seq in WTC11 human iPSCs.
| Accession | PRJNA702102; GEO: GSE166837 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Ren X et al., "Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath.", Sci Adv, 2021 Sep 17;7(38):eabi4360 |
| Submission | Registration date: 16-Feb-2021
Shen Lab, Department of Neurology, UCSF |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 2 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 2 |
| GEO DataSets | 1 |