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Accession: PRJNA668384 ID: 668384

Host-informed molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine [Ribo-seq]

See Genome Information for Komagataella phaffii
We analyzed total RNA and ribosome footprints collected from a K. phaffii strain secreting the VP8-P[6] serotype of the rotavirus antigen and compared against a strain secreting the VP8-P[4] serotype for reference. More...
AccessionPRJNA668384; GEO: GSE159336
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismKomagataella phaffii[Taxonomy ID: 460519]
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Pichiomycetes; Pichiales; Pichiaceae; Komagataella; Komagataella phaffii
PublicationsDalvie NC et al., "Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus.", Microb Cell Fact, 2021 May 1;20(1):94
SubmissionRegistration date: 9-Oct-2020
Koch Institute
RelevanceUnknown
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments8
Publications
PubMed1
PMC1
Other datasets
BioSample8
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes37
SRA Data Details
ParameterValue
Data volume, Gbases19
Data volume, Mbytes8184

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