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Accession: PRJNA419768 ID: 419768

E. coli MazF does not create specialized ribosomes that translate leaderless mRNAs, but instead blocks rRNA maturation and ribosome biogenesis [Ribo-Seq]

See Genome Information for Escherichia coli
The purpose of this experiment was to assess translation of mRNA after MazF expression to determine if cleavage events resulted in a loss in ribosome footprints. More...
AccessionPRJNA419768; GEO: GSE107328
ScopeMultiisolate
OrganismEscherichia coli[Taxonomy ID: 562]
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli
PublicationsCulviner PH et al., "Global Analysis of the E. coli Toxin MazF Reveals Widespread Cleavage of mRNA and the Inhibition of rRNA Maturation and Ribosome Biogenesis.", Mol Cell, 2018 Jun 7;70(5):868-880.e10
SubmissionRegistration date: 24-Nov-2017
Laub, Biology, MIT
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments3
Publications
PubMed1
PMC1
Other datasets
BioSample3
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes27
SRA Data Details
ParameterValue
Data volume, Gbases18
Data volume, Mbytes7478

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