U.S. flag

An official website of the United States government

Display Settings:

Format

Send to:

Choose Destination
Accession: PRJNA353310 ID: 353310

Screening GeCKO lentiCRISPR knockout sgRNA library in human Fireworks HeLa cells to identify components and regulators of the human nonsense-mediated mRNA decay pathway.

We developed a method of in vivo amplification of NMD reporter fluorescence (Fireworks) that enables CRISPR-based forward genetic screening for NMD pathway defects in human cells. More...
AccessionPRJNA353310
Data TypeRaw sequence reads
ScopeMultispecies
Grants
  • "VERTEBRATE NON-CODING RNPS: INTEGRATING FUNCTION, BIOGENESIS AND SURVIVAL" (Grant ID R01GM026154, National Institute of Health)
  • "IDENTIFICATION OF NEW HUMAN TARGETS TO INHIBIT DECAY OF PTC-CONTAINING MRNAS" (Grant ID R21NS091637, National Institute of Health)
SubmissionRegistration date: 13-Nov-2016
Yale University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments2
Other datasets
BioSample2
SRA Data Details
ParameterValue
Data volume, Gbases3
Data volume, Mbytes1354

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center