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Accession: PRJNA310000 ID: 310000

Homo sapiens (human)

Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells

See Genome Information for Homo sapiens
Notch signaling is an important regulator of stem cell differentiation. All canonical Notch signaling is transmitted through the DNA-binding protein CSL and hyperactivated Notch signaling is associated with tumor development; thus it may be anticipated that CSL deficiency should reduce tumor growth. More...
AccessionPRJNA310000; GEO: GSE77308
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsBraune EB et al., "Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells.", Stem Cell Reports, 2016 May 10;6(5):643-651
SubmissionRegistration date: 27-Jan-2016
Urban Lendahl, CMB, Karolinska Insitute
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments404
Publications
PubMed1
PMC1
Other datasets
BioSample404
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes26
SRA Data Details
ParameterValue
Data volume, Gbases51
Data volume, Mbytes51091

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    Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells
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