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Accession: PRJNA368917 ID: 368917

An Integrated Approach to Understanding Host-Pathogen Interactions

This Malaria Host-Pathogen Interaction Center (MaHPIC) is a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (# HHSN272201200031C, 2012-2017; see http://www.systemsbiology.emory.edu). The MaHPIC has continued with support from the Defense Advanced Research Project Agency (DARPA) and others. The MaHPIC generates many data types (e.g., clinical, hematological, parasitological, metabolomics, functional genomics, lipidomics, proteomics, immune response, telemetry) and mathematical models, to iteratively test and develop hypotheses related to the complex host-parasite dynamics in the course of malaria in non-human primates (NHPs), and metabolomics data via collaborations with investigators conducting clinical studies in malaria endemic countries, with the overarching goal of better understanding human disease, pathogenesis, and immunity. Curation and maintenance of all data and metadata are the responsibility of the MaHPIC.
AccessionPRJNA368917
TypeUmbrella project
SubmissionRegistration date: 26-Jan-2017
Malaria Host-Pathogen Interaction Center
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
Nucleotide (total)45
WGS master1
Genomic DNA16
SRA Experiments572
Protein Sequences10733
Publications
PubMed2
PMC2
Other datasets
BioSample558
GEO DataSets14
Assembly2
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes364
SRA Data Details
ParameterValue
Data volume, Gbases7,310
Data volume, Tbytes3.50
This project encompasses the following 16 sub-projects:
Project TypeNumber of Projects
Genome sequencing
Highest level of assembly :
Chromosomes
Scaffolds
Total

1
1
2
BioProject
accession
Assembly
level
NameTitle
PRJNA315987 ChromosomesAn Integrated Approach to Understanding Host-Pathogen InteractionsAn Integrated Approach to Understanding Host-Pathogen Interactions (Malaria Host-Pathogen Interaction...)
PRJNA377737 ScaffoldsPlasmodium knowlesiPlasmodium knowlesi Pk1 (A+) Malayan H strain Genome Sequencing, Assembly, and Annotation (Malaria Host Pathogen Interaction...)
transcriptome14
BioProject
accession
OrganismTitle
PRJNA385819Macaca mulattaMalaria Host Pathogen Interaction Center Experiment 04: Host and parasite gene transcript abundances, from bone marrow aspirate, of Macaca mulatta infected Plasmodium cynomolgi treated with artemether over 7 time points in a 100 day study (GSE94273) (University of Georgia)
PRJNA385820Macaca mulattaAn Integrated Approach to Understanding Host-Pathogen Interactions (SuperSeries GSE94274) (University of Georgia)
PRJNA385821Macaca mulattaMalaria Host Pathogen Interaction Center: Gene and exon transcript abundances of uninfected Macaca mulatta treated with pyrimethamine over 7 time points in a 100 day study (GSE58340) (University of Georgia)
PRJNA388645Macaca mulattaMalaria Host Pathogen Interaction Center Experiment 04: Host and parasite gene transcript abundances, from whole blood, of Macaca mulatta infected Plasmodium cynomolgi treated with artemether over 7 time points in a 100 day study (GSE99486) (Emory University)
PRJNA400137Macaca mulattaMalaria Host Pathogen Interaction Center Experiment 03: Host and parasite gene transcript abundance measures from bone marrow for Macaca mulatta infected with Plasmodium coatneyi Hackeri strain from 7 time points over a 101 day study (GSE103042) (Emory University)
List all 14 'transcriptome' projects...

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