See
Genome Information for Mus musculus
To define the molecular response to JAKi treatment, we performed RNA-seq analysis on a series of skin biopsies taken before and after systemic treatment with INCB039110 (JAK1i), CEP-33779 (JAK2i), PF-06651600 (JAK3i), ruxolitinib (JAK1/2i), tofacitinib (pan-JAKi) or vehicle control.
Overall design: mRNA profiles to JAKi treatment of C3H/HeJ AA mice.
| Accession | PRJNA704387; GEO: GSE167360 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Dai Z et al., "Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata.", JCI Insight, 2021 Apr 8;6(7) |
| Submission | Registration date: 23-Feb-2021
Dermatology, Columbia University |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 24 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 24 |
| GEO DataSets | 1 |