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Accession: PRJNA640049 ID: 640049

The effect of natural feline coronavirus infection on the host immune response: a whole-transcriptome analysis on the mesenteric lymph nodes of cats with and without feline infectious peritonitis (domestic cat)

See Genome Information for Felis catus
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This project is a component of the INSDC Non-Human Coronavirus Host Sequencing Data
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70 additional projects are related by organism.
235 additional projects are components of the INSDC Non-Human Coronavirus Host Sequencing Data.
Purpose: Comparison of the effect on the host immune response of feline coronavirus infection with or without feline infectious peritonitis Results: FIP was associated with higher pro-inflammatory pathway enrichment; whilst non-FIP FCoV-positive cats showed lower enrichment of humoral immunity pathways, below that of uninfected cats in the case of immunoglobulin production pathways Conclusions: Reinforces host differences in disease susceptibility in addition to any viral factors, importance of cellular vs humoral response also highlighted. More...
AccessionPRJNA640049; GEO: GSE152676
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismFelis catus[Taxonomy ID: 9685]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis; Felis catus
SubmissionRegistration date: 17-Jun-2020
Functional Genomics Center Zurich, ETH/University of Zurich
RelevanceUnknown
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments24
Other datasets
BioSample24
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Gbases64
Data volume, Mbytes19540

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