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Accession: PRJNA638386 ID: 638386

Multiplexed functional assessment of dominant genetic variants in CARD11 (human)

See Genome Information for Homo sapiens
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66644 additional projects are related by organism.
We describe the use of saturation genome editing to measure the effects of CARD11 variants on protein function, splicing and lymphoma cell survival. More...
AccessionPRJNA638386; GEO: GSE152129
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMeitlis I et al., "Multiplexed Functional Assessment of Genetic Variants in CARD11.", Am J Hum Genet, 2020 Dec 3;107(6):1029-1043
Grants
  • "Mechanisms mediating resistance to ibrutinib in Non-Hodgkin's lymphoma" (Grant ID R01 CA201135, National Cancer Institute)
SubmissionRegistration date: 9-Jun-2020
Seattle Children's Research Institute
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments147
Publications
PubMed1
PMC1
Other datasets
BioSample147
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Gbases50
Data volume, Mbytes20364

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