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Accession: PRJNA638166 ID: 638166

TT-TL-seq reveals transcriptional profiles that accompany DoG induction after hyperosmotic stress. (human)

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This project is a component of the Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repression
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2 additional projects are components of the Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repression.
66644 additional projects are related by organism.
TT-TimeLapse-seq was used to investigate the nascent transcription profiles that accompany the induction of downstream-of-gene (DoG) containing transcripts in human cell lines. More...
AccessionPRJNA638166; GEO: GSE152059
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsRosa-Mercado NA et al., "Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression.", Mol Cell, 2021 Feb 4;81(3):502-513.e4
SubmissionRegistration date: 8-Jun-2020
Joan A. Steitz, Molecular Biophysics and Biochemistry, Yale University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes3733
SRA Data Details
ParameterValue
Data volume, Gbases82
Data volume, Mbytes25105

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