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Accession: PRJNA638132 ID: 638132

RNA-targeting Cas9 corrects molecular and physiological features in pre-clinical model of myotonic dystrophy type 1 (house mouse)

See Genome Information for Mus musculus
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In this Study, we used RNA-targeting Cas9 (RCas9) to reverse characteristic Myotonic Dystrophy (DM1) cellular phenotypes such as elimination of RNA foci, MBNL relocalization, and reversal of transcriptome-wide splicing in a mouse model of myotonic Dystrophy (DM1). More...
AccessionPRJNA638132; GEO: GSE152033
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
SubmissionRegistration date: 8-Jun-2020
UCSD
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments14
Other datasets
BioSample14
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes7
SRA Data Details
ParameterValue
Data volume, Gbases160
Data volume, Mbytes73044

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