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Genome Information for Mus musculus
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2 additional projects are components of the SOX2 is required independently in both stem and differentiated cells for pituitary tumor genesis in p27 null mice.
Exploration of the molecular mechanisms underlying melanotroph tumourigenesis and the role of SOX2 in both SCs and melanotrophs
Overall design: Single cell RNA sequencing analysis on pituitary intermediate lobe dissected from three-month old tamoxifen treated Sox9iresCreERT2/+;p27-/- , Sox9iresCreERT2/+;Sox2fl/+;p27-/- animals and control Sox9iresCreERT2/+ animals.
| Accession | PRJNA638094; GEO: GSE152009 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Moncho-Amor V et al., "SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice.", Proc Natl Acad Sci U S A, 2021 Feb 16;118(7) |
| Submission | Registration date: 8-Jun-2020
Francis Crick Institute |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 3 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 3 |
| GEO DataSets | 1 |