BRD4 Prevents the Accumulation of R-loops and Prot... (ID 634473) - BioProject

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Accession: PRJNA634473 ID: 634473

BRD4 Prevents the Accumulation of R-loops and Protects Against Transcription-Replication Collision Events and DNA Damage (human)

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Brd4 is essential in enhancing productive polII elongation along gene bodies. More...

Accession	PRJNA634473; GEO: GSE151038
Data Type	Epigenomics
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Lam FC et al., "BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage.", Nat Commun, 2020 Aug 14;11(1):4083
Grants	"Protein Kinase Signaling and Cell Cycle Control" (Grant ID R01 ES015339, National Institute of Environmental Health Sciences) "Protein Kinase Signaling in the Genotoxic Stress Response" (Grant ID R35 ES028374, National Institute of Environmental Health Sciences) "RNA-Binding Proteins as Molecular Integrators that Control the Response of HGSOC to Ant-Cancer Therapies" (Grant ID R01 CA226898, National Cancer Institute)
Submission	Registration date: 22-May-2020 76-353, Koch Institute, MIT
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	3826

Parameter	Value
Data volume, Gbases	70
Data volume, Mbytes	25850

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BRD4 Prevents the Accumulation of R-loops and Protects Against Transcription-Rep...
BRD4 Prevents the Accumulation of R-loops and Protects Against Transcription-Replication Collision Events and DNA Damage
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