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Genome Information for Homo sapiens
To understand the functional impact of aneuploidy in phenotypically normal cells, we induced aneuploidization by inhibiting spindle assembly checkpoint in hTERT-immortalized human mammary epithelial and renal tubular epithelial cells.
More...To understand the functional impact of aneuploidy in phenotypically normal cells, we induced aneuploidization by inhibiting spindle assembly checkpoint in hTERT-immortalized human mammary epithelial and renal tubular epithelial cells. After single-cell isolation, clones were cultured for a long-term to study their karyotypic evolution and their impact on growth properties. A number of clones were sequenced for their genomic DNA and mRNA to understand the impact of aneuploidy in mutagenesis and transcriptional profile.
Less...| Accession | PRJNA634423 |
| Data Type | Genome sequencing and assembly, Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Submission | Registration date: 21-May-2020
Harvard Medical School |
| Relevance | Medical |
| Locus Tag Prefix | HPY37 |
Project Data:
| Resource Name | Number
of Links |
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| BioSample | 1 |
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