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Accession: PRJNA578748 ID: 578748

CN133 hampers tumor growth in patient-derived pediatric ependymoma models (human)

See Genome Information for Homo sapiens
HDACs are known to play crucial roles in cancer by deacetylating histones and non-histone substrates, leading to altered expression of genes involved in several cellular processes such as cell cycle control, apoptosis, DNA-damage response, angiogenesis, and autophagy, among othersto caracterize the transcriptomic changes induced by CN133 treatment on EPN cells, a microarray expression analysis of the EPP cell line treated with CN133 was performed Overall design: Epp cell lines were treated for 5h with vehicle or CN133 at 1uM concentration. 3 samples were performed for each condictions
AccessionPRJNA578748; GEO: GSE139210
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 21-Oct-2019
roberta antonelli, VHIR barcelona
RelevanceMedical
Project Data:
Resource NameNumber
of Links
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots146106
Data volume, Processed Mbytes4
Data volume, Supplementary Mbytes8

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