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Accession: PRJNA577469 ID: 577469

Single-cell functional pharmacogenomics reveal cell decision information within gene expression noise (human)

See Genome Information for Homo sapiens
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66644 additional projects are related by organism.
Single HeLa cells were treated with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL, 25ng/ml, 50min) to determine their response profiles (“high” or “low”) by live-cell microscopy using a FRET sensor of capase-8 dynamics, a predictor of “cell death” or “cell survival”, respectively. More...
AccessionPRJNA577469; GEO: GSE138832
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMeyer M et al., "Profiling the Non-genetic Origins of Cancer Drug Resistance with a Single-Cell Functional Genomics Approach Using Predictive Cell Dynamics.", Cell Syst, 2020 Oct 21;11(4):367-374.e5
SubmissionRegistration date: 14-Oct-2019
Functional Genomics Platform of Nice-Sophia-Antipolis, France., IPMC/CNRS
RelevanceMedical
Project Data:
Resource NameNumber
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Sequence data
SRA Experiments19
Publications
PubMed1
Other datasets
BioSample19
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases4
Data volume, Mbytes819

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