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Accession: PRJNA524181 ID: 524181

Gene regulation by TLR2 and TLR10 in oncogene-induced senescence (human)

See Genome Information for Homo sapiens
In the present study, we analyse the effect of knocking down TLR2 and TLR10 during oncogene induced senescence in IMR90 cells expressing a inducible version of oncogenic RAS (ER:RAS) in the transcriptome using Ampliseq RNA sequencig. More...
AccessionPRJNA524181; GEO: GSE127116
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsHari P et al., "The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype.", Sci Adv, 2019 Jun;5(6):eaaw0254
SubmissionRegistration date: 5-Nov-2019
Cancer Research UK - Edinburgh Centre, The University of Edinburgh
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments21
Publications
PubMed1
PMC1
Other datasets
BioSample21
GEO DataSets1
SRA Data Details
ParameterValue
Data volume, Gbases27
Data volume, Mbytes14042

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