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Accession: PRJNA523802 ID: 523802

Combinatorial inhibition of Notch and FLT3 exerts synergistic cytotoxic effects in FLT3/ITD+ acute myeloid leukemia (human)

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we observed synergistic cytotoxic effects, preferentially reducing cell proliferation and inducing apoptosis in FLT3/ITD+ AML cell lines and in primary AML cells. More...
AccessionPRJNA523802; GEO: GSE126933
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsLi D et al., "Combined inhibition of Notch and FLT3 produces synergistic cytotoxic effects in FLT3/ITD+ acute myeloid leukemia.", Signal Transduct Target Ther, 2020 Mar 13;5(1):21
SubmissionRegistration date: 22-Feb-2019
Tongji Hospital
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments16
Publications
PubMed1
PMC1
Other datasets
BioSample16
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes50
SRA Data Details
ParameterValue
Data volume, Gbases19
Data volume, Mbytes10902

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