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Accession: PRJNA523738 ID: 523738

Nascent RNA sequencing (PRO-seq) after rapid degradation of AID-tagged ZNF143 (human)

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66644 additional projects are related by organism.
These experiments identify the primary response genes of ZNF143 in HEK-293T cells and the transcriptional response that results from treating cells with 500μM auxin. More...
AccessionPRJNA523738; GEO: GSE126919
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications
  • Smith JP et al., "PEPPRO: quality control and processing of nascent RNA profiling data.", Genome Biol, 2021 May 15;22(1):155
  • Sathyan KM et al., "An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion.", Genes Dev, 2019 Oct 1;33(19-20):1441-1455
Grants
  • "Mechanisms of coordinate gene regulation by transcription factors" (Grant ID R35 GM128635, National Institute of General Medical Sciences)
SubmissionRegistration date: 22-Feb-2019
Molecular Genomics, Center for Cell Analysis and Modeling, University of Connecticut
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments24
Publications
PubMed2
PMC2
Other datasets
BioSample24
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes783
SRA Data Details
ParameterValue
Data volume, Gbases63
Data volume, Mbytes25134

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