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Accession: PRJNA522789 ID: 522789

Investigation of transcriptional changes in cells expressing different levels of MeCP2 (human)

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3 additional projects are components of the Study of MeCP2 in LUHMES-derived neurons.

MeCP2 is transcriptional regulator, however the mechanism is not fully understood. More...

Accession	PRJNA522789; GEO: GSE126640
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Connelly JC et al., "Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo.", Nucleic Acids Res, 2020 Apr 17;48(7):3542-3552 Cholewa-Waclaw J et al., "Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic.", Proc Natl Acad Sci U S A, 2019 Jul 23;116(30):14995-15000
Submission	Registration date: 15-Feb-2019 Bioinformatics Core Facility, Wellcome Trust Centre for Cell Biology, University of Edinburgh
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	24056

Parameter	Value
Data volume, Gbases	954
Data volume, Tbytes	0.62

Supplemental Content

Investigation of transcriptional changes in cells expressing different levels of...
Investigation of transcriptional changes in cells expressing different levels of MeCP2
Investigation of transcriptional changes in cells expressing different levels of MeCP2

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