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Accession: PRJNA522474 ID: 522474

Loss of Bap1 leads to an increased global methylation and decrease in H3K27AC enhancer marks around key lineage commitment genes in Xenopus laevis embryos [ChIP-seq] (African clawed frog)

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This project is a component of the Loss of Bap1 in Xenopus laevis embryos
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1 additional project is a component of the Loss of Bap1 in Xenopus laevis embryos.
231 additional projects are related by organism.
We performed morpholino-mediated knockdown of Bap1 protein expression in Xenopus laevis developing embryos, and analyzed inhibiting and activating histone marks . More...
AccessionPRJNA522474; GEO: GSE126598
Data TypeEpigenomics
ScopeMultiisolate
OrganismXenopus laevis[Taxonomy ID: 8355]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus; Xenopus laevis
PublicationsKuznetsov JN et al., "BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers.", Sci Adv, 2019 Sep;5(9):eaax1738
SubmissionRegistration date: 14-Feb-2019
Harbour, Ophthalmology, University of Miami Miller School of Medicine
RelevanceModel Organism
Project Data:
Resource NameNumber
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Sequence data
SRA Experiments20
Publications
PubMed1
PMC1
Other datasets
BioSample20
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2229
SRA Data Details
ParameterValue
Data volume, Gbases49
Data volume, Mbytes19097

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