See
Genome Information for Homo sapiens
Identification of gene expression changes following inhibition of GSK-3 in Burkitt lymphoma
Overall design: We profiled cells treated for 0, 3, and 6 hours with the GSK-3 inhibitor CHIR99021 in biological triplicates
| Accession | PRJNA522272; GEO: GSE126529 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Harrington CT et al., "Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.", Leukemia, 2019 Oct;33(10):2429-2441 |
| Grants | - "The Myc - miR-17-92 axis in colorectal cancers" (Grant ID R01 CA196299, National Cancer Institute)
- "GSK3 inhibition as an adjuvant therapy for Burkitt's lymphoma" (Grant ID R21 CA183445, National Cancer Institute)
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| Submission | Registration date: 13-Feb-2019
Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 9 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 9 |
| GEO DataSets | 1 |