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Accession: PRJEB30090 ID: 522163

RNA-seq profiling of NSCLC cell lines exposed to the PARP inhibitor talazoparib.

An isogenic model of ERCC1-deficiency derived from the A549 NSCLC cell line was used for this study; this model consists of an ERCC1-wildtype parental cell line and an ERCC1-knockout cell line that was generated by zinc-finger targeting of ERCC1 gene. More...
AccessionPRJEB30090
ScopeMonoisolate
PublicationsChabanon RM et al., "PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer.", J Clin Invest, 2019 Mar 1;129(3):1211-1228
SubmissionRegistration date: 13-Feb-2019
INSTITUT GUSTAVE ROUSSY
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments24
Publications
PubMed1
PMC1
Other datasets
BioSample24
SRA Data Details
ParameterValue
Data volume, Gbases59
Data volume, Mbytes20832

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