The Mediterranean mussel is a widespread commercially, socially and ecologically important edible marine bivalve. Although pathogens and environmental alterations cause recurrent massive mortalities in other cultured species, mussels are extremely resilient to such conditions. Unfortunately, currently available genomics resources for this species are too limited to support molecular studies and improve farming practices. Here we report a high quality 1.28 Gb genome sequence, obtained through a tailored assembly strategy designed to overcome the inherent complexity of the mussel genome. We show that mussels display one of the highest levels of heterozygosity among metazoans and reveal that widespread genomic structural variations and gene presence/absence variability (PAV) are the main factors underlying the high levels of intraspecific genetic diversity observed.
More...The Mediterranean mussel is a widespread commercially, socially and ecologically important edible marine bivalve. Although pathogens and environmental alterations cause recurrent massive mortalities in other cultured species, mussels are extremely resilient to such conditions. Unfortunately, currently available genomics resources for this species are too limited to support molecular studies and improve farming practices. Here we report a high quality 1.28 Gb genome sequence, obtained through a tailored assembly strategy designed to overcome the inherent complexity of the mussel genome. We show that mussels display one of the highest levels of heterozygosity among metazoans and reveal that widespread genomic structural variations and gene presence/absence variability (PAV) are the main factors underlying the high levels of intraspecific genetic diversity observed. Moreover, we show that the ~15,000 mussel dispensable genes are enriched in functions related to immune defense and survival. This unique genomic trait might explain the impressive capabilities of adaptation and invasiveness of this species.
Less...| Accession | PRJEB25156 |
| Type | Umbrella project |
| Submission | Registration date: 13-Feb-2019
Centro Nacional de Análisis Genómico |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| Nucleotide (total) | 10570 |
| WGS master | 1 |
| SRA Experiments | 191 |
| Protein Sequences | 78735 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 20 |
| Assembly | 1 |
Mussel's genomics encompasses the following 2 sub-projects:
| Project Type | Number of Projects |
Genome sequencingHighest level of assembly : Scaffolds |
1
|
BioProject
accession | Assembly
level | Name | Title |
|---|
| PRJEB24883 | Scaffolds | Mussel's genome | Widespread presence/absence gene variation points to an adaptive pan-genome in Mytilus galloprovincialis (Centro Nacional de Análisis...) |
|
| Other | 1 |
BioProject
accession | Name | Title |
|---|
| PRJEB25106 | Mussel resequencing data | Widespread presence/absence gene variation points to an adaptive pan-genome in Mytilus galloprovincialis (Centro Nacional de Análisis...) |
|