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1 additional project is a component of the The chromosomal protein SMCHD1 regulates DNA methylation by antagonizing TET proteins.
We performed the whole genome bisulfite sequencing to detect the DNA methylation between the wild type ES cells and Smchd1 mutant ES cells
Overall design: Three biological replicates per genotype; DNA was isolated individually from each replicate; three samples for WT and Smchd-KO mutant were sequenced twice.
| Accession | PRJNA521987; GEO: GSE126466 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Huang Z et al., "The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins.", Sci Adv, 2021 Jan;7(4) |
| Submission | Registration date: 12-Feb-2019
Center for Epigenetics, Van Andel Research Institute |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 6 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 6 |
| GEO DataSets | 1 |