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Accession: PRJNA521486 ID: 521486

Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes [AT_MC] (house mouse)

See Genome Information for Mus musculus
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This project is a component of the Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes
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3 additional projects are components of the Platinoid drugs augment immunotherapy via histone acetylation of MHCI machinery genes.
47588 additional projects are related by organism.
Here we show that low dose Oxali, and to a lesser extent other platinoids, can uniquely activate the transcriptional program that controls MHCI antigen processing and presentation. More...
AccessionPRJNA521486; GEO: GSE126287
Data TypeEpigenomics
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsZhou Y et al., "Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation.", Proc Natl Acad Sci U S A, 2021 Feb 23;118(8)
SubmissionRegistration date: 8-Feb-2019
Pharmacology, UCSD-School of Medicine
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments10
Publications
PubMed1
PMC1
Other datasets
BioSample10
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes27
SRA Data Details
ParameterValue
Data volume, Gbases50
Data volume, Mbytes23701

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