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Accession: PRJNA521482 ID: 521482

RNA Sequencing Analysis of macrophage and CD4+T cells from Wild Type and Gsdmd-/- mice (house mouse)

See Genome Information for Mus musculus
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47588 additional projects are related by organism.
We identified that GSDMD was required for the pathogenesis of EAE, and GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS , leading to the suppression of neuroinflammation and demyelination. More...
AccessionPRJNA521482; GEO: GSE126289
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLi S et al., "Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.", J Exp Med, 2019 Nov 4;216(11):2562-2581
SubmissionRegistration date: 8-Feb-2019
Nanjing Medical University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases13
Data volume, Mbytes8007

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